Alcon Launches SYSTANE PRO Preservative-Free OTC Drops for Dry Eye in the US

Alcon claims the dry eye treatment is the longest-lasting OTC eye drop in the SYSTANE lineup.

A new dry eye drop has entered the Alcon (Geneva, Switzerland) line-up, and the company is touting it as among its best yet.

On Monday, the Swiss eye care giant announced the US launch of SYSTANE^® PRO Preservative-Free (PF), describing it as the longest-lasting over-the-counter eye drop for dry eye relief within the SYSTANE portfolio.¹

With a triple-action, preservative-free formula, SYSTANE PRO PF is designed to hydrate, restore tear film stability and protect against irritation—key factors in managing one of the most common ocular surface diseases.

“We are proud to introduce SYSTANE PRO PF, the first and only multi-dose preservative-free triple-action formula with hyaluronate, nano-sized lipids and HP-Guar that support the active ingredient, giving patients long-lasting relief from the symptoms of dry eye,” said Terry Kim, MD, chief medical officer and head of global medical safety at Alcon.

Dr. Selina McGee, founder and chief optometrist at Bespoke Vision (Oklahoma, United States), emphasized the benefits of this new formulation. “As an eye care professional and global dry eye expert, I know that patients should benefit from the design of a triple-action preservative-free formula that includes hyaluronate to address all types of dry eye.”

“SYSTANE PRO PF provides hydration and protection of the ocular surface and can also stabilize the lipid layer of the tear film to reduce evaporation and provide lasting dry eye relief for my patients,” she added.

SYSTANE PRO PF is available in the U.S. starting this month, with plans to expand to additional markets in 2026. The product will also be featured at the SECO International meeting in Atlanta, Georgia, this week (Feb 26-March 2).

Reference

Alcon. Alcon Announces U.S. Launch of New SYSTANE PRO Preservative-Free, Revolutionizing Dry Eye Relief With Its Longest Lasting Formula Yet, February 24, 2025. https://www.alcon.com/media-release/alcon-announces-us-launch-new-systane-pro-preservative-free-revolutionizing-dry-eye/. Accessed on February 24, 2025.